Deficiencia factor vii pdf

Incidencia 1 en 500,000 afecta a hombres y mujeres por igual. Factor ii, also known as prothrombin, is a protein made in. Kaczor, bs, mt2, and francois depasse, pharmd, msc1 abstract factor vii fvii deficiency is a rare inheritable bleeding disorder affecting 1500 000 individuals. Factor vii deficiency is a bleeding disorder characterized by a lack in the production of factor vii fvii proconvertin, a protein that causes blood to clot in the coagulation cascade. In factor vii deficiency, most commonly the human and ox tissue factors show the highest sensitivity to the coagulation defect, whereas the one extracted from rabbits is definitely less sensitive. The complex formed between the procoagulant serine protease activated factor vii fvii and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. Spanish multimedia encyclopedia deficiencia del factor vii. This booklet has been written in order to inform people with factor vii. Factor vii activado recombinante medicina intensiva. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. From basics to clinical laboratory diagnosis and patient management pierreolivier sevenet, pharmd1, daniel a. Factor vii fvii deficiency is a rare hereditary hemorrhagic disease caused by the diminution or absence of this coagulation factor.